Also known as:kidney parenchymal disease, renal parenchyma of the kidney, bilateral renal parenchyma diseases.

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What are renal parenchyma diseases?

The renal parenchyma is the functional part of the kidney that includes the renal cortex (the outermost part of the kidney) & the renal medulla.

The renal cortex contains the approximately 1 million nephrons (these have sầu glomeruli which are the primary filterer of blood passing through the kidney, và renal tubules which modify the fluid khổng lồ produce the appropriate amount/content of urine).The renal medulla consists primarily of tubules/ducts which are the beginning of the collecting system that allows the urine to lớn flow onwards khổng lồ being excreted.

Renal parenchyma disease describes medical conditions which damage these parts of the kidney. These diseases may be congenital, hereditary or acquired.

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What causes renal parenchyma diseases?

Causes vary và include:

hereditary conditions passed on from parentsbacterial và viral infectionshigh blood pressuremedications and others.

What are the signs/symptoms of renal parenchyma diseases?

As the kidneys regulate the amount of fluid in the toàn thân and adjust the salts in the blood lớn reflect metabolic activity, (plus other hormonal functions), comtháng signs include:

high blood pressureanemiabone changesblood in the urineabdominal swelling

Comtháng symptoms include loss of appetite, itching, nausea và vomiting, fatigue, joint pain, frequent night urination và dizziness.

What are renal parenchyma diseases care options?

Treatments depends on the underlying cause and controlling that, plus alleviating symptoms và preventing complications are the focus of management.

Medications, fluid management, attention lớn calorie intake, dietary changes, dialysis and possibly kidney transplantation are all frequently utilized.

Reviewed by: Jaông xã Wolfsdorf, MD, FAAP

This page was last updated on: March 24, 2021 01:59 PM


The Division of Nephrology at Nicklaus Children’s Hospital treats kidney disorders & provides comprehensive evaluation of renal functions, including kidney biopsies.

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